Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024131
Disease: Lupus Vulgaris
Lupus Vulgaris 		0.100 Biomarker BEFREE The expressions of vascular cellular adhesion molecule-1 (VCAM-1), intracellular adhesion molecule-1 (ICAM-1), interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and monocyte chemoattractant protein-1 (MCP-1) in MRL/lpr mouse glomerular endothelial cells (lupus-MGECs) were estimated by quantitative real-time polymerase chain reaction, enzyme-linked immunosorbent assay and Western blotting. 30268079

2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024131
Disease: Lupus Vulgaris
Lupus Vulgaris 		0.100 Biomarker BEFREE This study investigated the IL-6-hepcidin-hemoglobin axis in patients with lupus. 27416847

2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024131
Disease: Lupus Vulgaris
Lupus Vulgaris 		0.100 Biomarker BEFREE Lupus Skin Is Primed for IL-6 Inflammatory Responses through a Keratinocyte-Mediated Autocrine Type I Interferon Loop. 27646883

2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024131
Disease: Lupus Vulgaris
Lupus Vulgaris 		0.100 Biomarker BEFREE IL-1<i>β</i> and IL-6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythematous Subtype. 28286780

2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024131
Disease: Lupus Vulgaris
Lupus Vulgaris 		0.100 AlteredExpression BEFREE Lupus mice were established by confirming elevated levels of autoantibodies and IL-6 after intraperitoneal injection of pristane. 28303221

2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024131
Disease: Lupus Vulgaris
Lupus Vulgaris 		0.100 GeneticVariation BEFREE Genetic polymorphisms of interleukin 6 and interleukin 10 in Egyptian patients with systemic lupus eythematosus. 26568585

2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024131
Disease: Lupus Vulgaris
Lupus Vulgaris 		0.100 AlteredExpression BEFREE African American women with lupus had significantly higher serum levels of IL-6 and TNF-α. 24865418

2014
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024131
Disease: Lupus Vulgaris
Lupus Vulgaris 		0.100 Biomarker BEFREE We also measured the IL-6 concentration secreted by peripheral blood mononuclear cells (PBMCs) incubated with (a) oligonucleotide (CpG-B) in the presence or absence of recombinant human PGRN (rhPGRN); and (b) lupus sera in the presence or absence of a neutralizing anti-PGRN antibody. 23140401

2012
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024131
Disease: Lupus Vulgaris
Lupus Vulgaris 		0.100 GeneticVariation BEFREE The aim of this study is to investigate whether the IL-6 -174 G/C polymorphism associates with lupus susceptibility or affects disease characteristics in Portuguese patients with SLE. 21153673

2011
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024131
Disease: Lupus Vulgaris
Lupus Vulgaris 		0.100 AlteredExpression BEFREE IL-6 modulates CD5 expression in B cells from patients with lupus by regulating DNA methylation. 19380809

2009