Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.320 Biomarker BEFREE We verified MSLN expression in primary human GC tissues and GC cell lines and then redirected T cells with a CAR containing the MSLN scFv (single-chain variable fragment), CD3ζ, CD28, and DAP10 intracellular signaling domain (M28z10) to target MSLN. 30777106

2019

Entrez Id: 10232
Gene Symbol: MSLN
MSLN
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.320 AlteredExpression BEFREE Gastric cancer tissue also expresses C-ERC/mesothelin, but the significance of serum N-ERC levels for diagnosing gastric cancer has not yet been studied. 24146039

2014

Entrez Id: 10232
Gene Symbol: MSLN
MSLN
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.320 Biomarker CTD_human We described that the luminal membrane expression of mesothelin was a reliable prognostic factor in gastric cancer, suggesting the functional significance of membrane-localised mesothelin in the aggressive behaviour of gastric cancer cells. 22644300

2012