Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4162
Gene Symbol: MCAM
MCAM
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.310 Biomarker BEFREE Compared to the broad effects of VLA-4 blockade on encephalitogenic T cell migration over endothelial barriers, MCAM blockade impeded encephalitogenic T cell migration in murine models of MS that especially depend on CNS migration across the choroid plexus (CP). 30134924

2018
Entrez Id: 4162
Gene Symbol: MCAM
MCAM
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.310 Therapeutic CTD_human Moreover, treating both active and passive MS models with the anti-CD146 antibody AA98 significantly decreased the infiltrated lymphocytes in the CNS and decreased neuroinflammation. 23595028

2013