Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8882
Gene Symbol: ZPR1
ZPR1
CUI: C0026847
Disease: Spinal Muscular Atrophy
Spinal Muscular Atrophy 		0.050 AlteredExpression BEFREE ZPR1 overexpression in vivo results in a systemic increase of SMN levels and rescues severe to moderate disease in SMA mice. 31828288

2020
Entrez Id: 8882
Gene Symbol: ZPR1
ZPR1
CUI: C0026847
Disease: Spinal Muscular Atrophy
Spinal Muscular Atrophy 		0.050 Biomarker BEFREE Identification of ZPR1 and HoxA5 as potential targets provides a paradigm for developing strategies to treat respiratory distress in SMA. 28811488

2017
Entrez Id: 8882
Gene Symbol: ZPR1
ZPR1
CUI: C0026847
Disease: Spinal Muscular Atrophy
Spinal Muscular Atrophy 		0.050 Biomarker BEFREE ZPR1 stimulates neurite growth and rescues axonal growth defects in SMN-deficient spinal cord neurons from SMA mice. 22422766

2012
Entrez Id: 8882
Gene Symbol: ZPR1
ZPR1
CUI: C0026847
Disease: Spinal Muscular Atrophy
Spinal Muscular Atrophy 		0.050 AlteredExpression BEFREE We further demonstrate that a single low nanomolar dose of this 8-mer ASO substantially increases the levels of SMN and a host of factors including Gemin 2, Gemin 8, ZPR1, hnRNP Q and Tra2-beta1 known to be down-regulated in SMA. 19430205

2009
Entrez Id: 8882
Gene Symbol: ZPR1
ZPR1
CUI: C0026847
Disease: Spinal Muscular Atrophy
Spinal Muscular Atrophy 		0.050 Biomarker BEFREE Spinal muscular atrophy disrupts the interaction of ZPR1 with the SMN protein. 11283611

2001