Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2762
Gene Symbol: GMDS
GMDS
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.030 GeneticVariation BEFREE Mutation of GDP-mannose-4,6-dehydratase in colorectal cancer metastasis. 23922970

2013

Entrez Id: 2762
Gene Symbol: GMDS
GMDS
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.030 Biomarker BEFREE Recently, we found that a deficiency in GDP-mannose-4,6-dehydratase (GMDS) rendered colon cancer cells resistant to TRAIL-induced apoptosis, resulting in tumor development and metastasis by escape from tumor immune surveillance. 22027835

2011

Entrez Id: 2762
Gene Symbol: GMDS
GMDS
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.030 Biomarker BEFREE When mock and GMDS-rescued cells were transplanted into athymic mice, tumor growth and metastasis of the GMDS-rescued cells were dramatically suppressed through NK cell-mediated tumor surveillance. 19361506

2009