Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3082
Gene Symbol: HGF
HGF
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.360 AlteredExpression BEFREE The neuroblastoma SK-N-SH cells with HGF overexpression which activates MET signalling are sensitive to MET inhibitors. 31137515

2019
Entrez Id: 3082
Gene Symbol: HGF
HGF
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.360 Biomarker BEFREE Activation of the HGF-mediated MET pathway is involved in escape to selective VEGFR inhibition in neuroblastoma suggesting combined inhibition of MET and VEGFR signaling to reduce secondary resistance and enhanced invasiveness. 27922668

2017
Entrez Id: 3082
Gene Symbol: HGF
HGF
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.360 Biomarker BEFREE This study showed that concentrations of HGF and S-VEGF-A are elevated in patients with NB. 19661350

2009
Entrez Id: 3082
Gene Symbol: HGF
HGF
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.360 AlteredExpression BEFREE We show that sublethal doses of irradiation up-regulated the expression of the hepatocyte growth factor (HGF) and its receptor c-Met in some neuroblastoma cell lines. 15809092

2005
Entrez Id: 3082
Gene Symbol: HGF
HGF
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.360 AlteredExpression BEFREE We conclude that TrkB expression in neuroblastoma cells results in an increase in their invasive capability via upregulated expression of HGF/c-Met and enhanced activity of proteolytic networks. 16051641

2005
Entrez Id: 3082
Gene Symbol: HGF
HGF
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.360 Biomarker CTD_human The neurotrophin receptor TrkB cooperates with c-Met in enhancing neuroblastoma invasiveness. 16051641

2005
Entrez Id: 3082
Gene Symbol: HGF
HGF
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.360 Biomarker BEFREE We show that HGF stimulates invasion of neuroblastoma cells in vitro and in vivo, and it promotes the formation of angiogenic neuroblastomas in vivo. 15342394

2004