Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 470
Gene Symbol: ATHS
ATHS
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.060 AlteredExpression BEFREE The expression levels of osteoporosis-related genes (ALP, OCN, and OPN) were found to be decreased in hBMSCs treated with sh-BMP1. 30638953

2019
Entrez Id: 470
Gene Symbol: ATHS
ATHS
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.060 AlteredExpression BEFREE BMSCs in OP mice transfected with miR-196a mimic or si-GNAS displayed the elevated expression of Smo, ALP, Runx2, and OPN, as well as bone gla protein and tartrate-resistant acid phosphatase, elevated ALP vitality and bone formation ability as well as reduced expression of GNAS and PTCH. 31452264

2019
Entrez Id: 470
Gene Symbol: ATHS
ATHS
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.060 AlteredExpression BEFREE Decreased Runx2 expression and ALP activity were found after treatment of MSCs-derived exosomes extracted from osteoporosis patients. 30338786

2018
Entrez Id: 470
Gene Symbol: ATHS
ATHS
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.060 AlteredExpression BEFREE Furthermore, the expression of ALP mRNA and ALP activity in bone tissue were much higher in osteoporosis patients with fracture than those without fracture. 29786747

2018
Entrez Id: 470
Gene Symbol: ATHS
ATHS
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.060 AlteredExpression BEFREE ALP levels in Osteoporosis group (112.06 ± 62.05 U/L) were significantly upregulated compared with Normal group (80.22 ± 14.94 U/L, <i>p</i> < 0.05). 28620614

2017
Entrez Id: 470
Gene Symbol: ATHS
ATHS
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.060 GeneticVariation BEFREE Lumbar spine osteoporosis was independently associated with lower BMI (OR 0.73, 95% CI 0.54-0.94), total ALP (OR 1.17, 95% CI 1-1.39 per 10 unit increase) and the amount of iron removed (OR 1.53, 95% CI 1-2.5 per 5 g increase). 18661088

2009