Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0031069
Disease: Familial Mediterranean Fever
Familial Mediterranean Fever 		0.060 AlteredExpression BEFREE This study aimed to examine the IL-1β, IL-1ra, and IL-10 cytokine levels in gingival crevicular fluid (GCF) and serum of familial Mediterranean fever (FMF) and chronic periodontitis (CP) patients, and their response to nonsurgical periodontal therapy. 27068409

2017
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0031069
Disease: Familial Mediterranean Fever
Familial Mediterranean Fever 		0.060 GeneticVariation BEFREE There was no significant difference in IL-1Ra genotype and allele distributions between FMF and the control groups (p>0.05). 26861613

2016
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0031069
Disease: Familial Mediterranean Fever
Familial Mediterranean Fever 		0.060 Biomarker BEFREE The balance between the pro-inflammatory cytokine IL-1β and its receptor antagonist IL-1RA plays an important role in the development of FMF. 26585190

2015
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0031069
Disease: Familial Mediterranean Fever
Familial Mediterranean Fever 		0.060 Biomarker BEFREE Freshly isolated monocytes from 21 patients with FMF (12 homozygous and 9 heterozygous), 14 MEFV healthy carriers and 30 healthy donors (HDs), unstimulated or after lipopolysaccharide (LPS)-induced activation, were analysed for redox state (production of reactive oxygen species (ROS) and antioxidant responses) and IL-1β and IL-1 receptor antagonist (IL-1Ra) secretion. 23505242

2014
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0031069
Disease: Familial Mediterranean Fever
Familial Mediterranean Fever 		0.060 GeneticVariation BEFREE IL-1Beta-511 (C/T), IL-1Beta+3953 (C/T) and IL-1Ra VNTR polymorphisms are not associated with the development of amyloid in FMF patients. 19026124

2009
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0031069
Disease: Familial Mediterranean Fever
Familial Mediterranean Fever 		0.060 GeneticVariation BEFREE IL-1beta-511 (C/T), IL-1beta+3953 (C/T) and IL-1Ra VNTR polymorphisms were not associated with the development of amyloid in FMF patients. 19339884

2009