Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3606
Gene Symbol: IL18
IL18
CUI: C0031069
Disease: Familial Mediterranean Fever
Familial Mediterranean Fever 		0.030 Biomarker BEFREE IL-1β and IL-18 released by monocytes from healthy donors (HDs) and FMF patients were measured upon specific engagement of the Pyrin, NLRP3 and NLRC4 inflammasomes. 29040788

2018
Entrez Id: 3606
Gene Symbol: IL18
IL18
CUI: C0031069
Disease: Familial Mediterranean Fever
Familial Mediterranean Fever 		0.030 GeneticVariation BEFREE We serially evaluated serum levels of pro-inflammatory cytokines, including IL-18, in 12 patients with FMF carrying exon 10 mutations, all of whom showed typical FMF attacks. 29017770

2018
Entrez Id: 3606
Gene Symbol: IL18
IL18
CUI: C0031069
Disease: Familial Mediterranean Fever
Familial Mediterranean Fever 		0.030 AlteredExpression BEFREE This report describes 2 molecules secreted by unconventional secretory pathways, S100A12 and IL-18, whose concentrations correlated with clinical disease activity and genotype in patients with FMF. 27333294

2016