Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.150 AlteredExpression BEFREE Meanwhile, TLR4 expression on the epithelial membranes of AE skin was increased compared with psoriasis skin (P<0.01). 28713916

2017
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.150 GeneticVariation BEFREE We present data suggestive of an association between a functional variant and an intronic variant of TLR4 and chronic plaque type psoriasis and psoriatic arthritis. 26830904

2016
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.150 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.150 AlteredExpression BEFREE Increased gene expression of Toll-like receptor 4 on peripheral blood mononuclear cells in patients with psoriasis. 23457721

2013
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.150 AlteredExpression BEFREE Monocytes and monocyte-derived dendritic cells (DCs) from symptomatic (n = 12) and asymptomatic atopic donors (n = 11), healthy nonatopics (n = 14) and from patients with psoriasis (n = 13) were analyzed for their expression of TLR2, TLR4 and TLR9 by real-time PCR. 22555189

2012
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.150 Biomarker BEFREE Only a few genes were differentially induced in psoriasis (CLEC7A (dectin-1), Toll-like receptor (TLR) 4, and mannose receptor C type 1 (MRC1)) or AD (MRC1, IL1RN, and IL1β) compared with normal epidermis. 20631729

2010