Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.370 Biomarker CTD_human Aberrant expression of miR-125a-3p promotes fibroblast activation via Fyn/STAT3 pathway during silica-induced pulmonary fibrosis. 30658076

2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.370 AlteredExpression BEFREE The activity of AKT in lung tissue was suppressed, but conversely, the activity of STAT3 was enhanced during lung fibrosis in mice. 31049028

2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.370 Biomarker BEFREE Aberrant expression of miR-125a-3p promotes fibroblast activation via Fyn/STAT3 pathway during silica-induced pulmonary fibrosis. 30658076

2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.370 Biomarker BEFREE CXCL16 Induces the Progression of Pulmonary Fibrosis through Promoting the Phosphorylation of STAT3. 31379980

2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.370 Biomarker BEFREE PD-1 up-regulation on CD4<sup>+</sup> T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production. 30257954

2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.370 Biomarker BEFREE Our results identify novel genes essential for the myofibroblast phenotype, and point to STAT3 as an important target in pulmonary fibrosis and other fibrotic diseases. 29678906

2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.370 AlteredExpression BEFREE The signal transducer and activator of transcription 3 (STAT3) protein is activated in lung fibroblasts and alveolar type II cells (ATII), thereby contributing to lung fibrosis in IPF. 29409529

2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.370 AlteredExpression BEFREE Collectively, our results demonstrate that by decreasing IFN-γ-induced STAT3/p-STAT3 expression to down-regulate miR-21, sulindac could significantly reverse EMT in A549 cells and prevent BLM-induced PF. 25704671

2015