Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1406
Gene Symbol: CRX
CRX
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		0.060 Biomarker BEFREE Cone and cone-rod dystrophies (CD and CRD, respectively) are degenerative retinal diseases that predominantly affect the cone photoreceptors. 29184169

2018
Entrez Id: 1406
Gene Symbol: CRX
CRX
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		0.060 GeneticVariation BEFREE Human CRX mutations can cause dominant retinopathies of varying onset and phenotype severity. 28903150

2017
Entrez Id: 1406
Gene Symbol: CRX
CRX
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		0.060 Biomarker BEFREE These animal models also reveal unexpected pathogenic mechanisms underlying CRX-associated retinopathies. 24888636

2014
Entrez Id: 1406
Gene Symbol: CRX
CRX
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		0.060 GeneticVariation BEFREE Mutations in human CRX are associated with the dominant retinopathies Retinitis Pigmentosa (RP), Cone-Rod Dystrophy (CoRD) and Leber Congenital Amaurosis (LCA), with variable severity. 24516401

2014
Entrez Id: 1406
Gene Symbol: CRX
CRX
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		0.060 Biomarker BEFREE In addition, it demonstrates the effectiveness of CRX-based cis-regulatory mapping in prioritizing candidate genes from exome data and suggests that this strategy should be generally applicable to a range of retinal diseases. 21835304

2011
Entrez Id: 1406
Gene Symbol: CRX
CRX
CUI: C0035309
Disease: Retinal Diseases
Retinal Diseases 		0.060 GeneticVariation BEFREE Truncation mutations in CRX are associated with retinopathies that share phenotypic features but vary in disease severity. 9804150

1998