Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10013
Gene Symbol: HDAC6
HDAC6
CUI: C0035372
Disease: Rett Syndrome
Rett Syndrome 		0.020 Biomarker BEFREE This Perspective outlines the application of HDAC(6) inhibitors in rare diseases, such as Rett syndrome, inherited retinal disorders, idiopathic pulmonary fibrosis, and Charcot-Marie-Tooth disease, highlighting their therapeutic potential as innovative and targeted disease-modifying agents. 31415174

2020
Entrez Id: 10013
Gene Symbol: HDAC6
HDAC6
CUI: C0035372
Disease: Rett Syndrome
Rett Syndrome 		0.020 Biomarker BEFREE We have interrogated the functional state of the microtubule network in fibroblasts derived from two patients with RTT as well as cortical neurons from a RTT mouse model and observed a reduction in acetylated α-tubulin and an increase in the tubulin-specific deacetylase, histone deacetylase 6 (HDAC6). 25209898

2015