Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23236
Gene Symbol: PLCB1
PLCB1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.540 Biomarker BEFREE The phosphodiesterase enzyme phospholipase C-β1 has been reported to be reduced in postmortem tissue of schizophrenia patients. 30517689

2019
Entrez Id: 23236
Gene Symbol: PLCB1
PLCB1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.540 GeneticVariation BEFREE Deletion of PLCB1 gene in schizophrenia-affected patients. 22507702

2012
Entrez Id: 23236
Gene Symbol: PLCB1
PLCB1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.540 AlteredExpression BEFREE Our data confirm that phospholipase C beta 1 transcript levels are decreased in the dorsolateral prefrontal cortex from subjects with schizophrenia. 21091263

2011
Entrez Id: 23236
Gene Symbol: PLCB1
PLCB1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.540 Biomarker BEFREE The most significant SNPs resided in ROR1 and PLCB1, genes known to be involved in bipolar disorder and schizophrenia, respectively. 21494683

2011
Entrez Id: 23236
Gene Symbol: PLCB1
PLCB1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.540 Biomarker MGD Phospholipase C-beta1 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration. 17667964

2008
Entrez Id: 23236
Gene Symbol: PLCB1
PLCB1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.540 Biomarker CTD_human Phospholipase C-beta1 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration. 17667964

2008