Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		0.330 Biomarker BEFREE Thus, SIRT1 may be a promising therapeutic target in the management of SSc-related pulmonary fibrosis. 28800254

2018
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		0.330 AlteredExpression BEFREE Sirt1, activated by resveratrol (Res), ameliorated cutaneous inflammation and fibrosis in bleomycin (BLM)-induced scleroderma mice. 28532580

2017
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		0.330 AlteredExpression BEFREE Cellular SIRT1 levels were suppressed in normal fibroblasts exposed to hypoxia or platelet-derived growth factor and were constitutively down-regulated in SSc fibroblasts. 25707573

2015
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
CUI: C0036421
Disease: Systemic Scleroderma
Systemic Scleroderma 		0.330 Therapeutic CTD_human The Histone Deacetylase Sirtuin 1 Is Reduced in Systemic Sclerosis and Abrogates Fibrotic Responses by Targeting Transforming Growth Factor β Signaling. 25707573

2015