Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.300 Biomarker CTD_human G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block. 26831068

2016

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 GeneticVariation BEFREE CALR, JAK2<sup>V617F</sup> and thrombopoietin receptor gene (MPL) mutations were analysed in a test cohort that included 312 patients with SVT. 28483676

2017

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 GeneticVariation BEFREE This meta-analysis provides new evidence supporting the conclusion that the JAK2 46/1 haplotype enrichment is significantly associated with the development of MPNs and SVT in these patients. 25015051

2014

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 GeneticVariation BEFREE Recent research has demonstrated in patients with MPN the existence of factors increasing the risk of SVT such as the presence of the JAK2 V617F mutation and its 46/1 haplotype. 23855810

2013

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 GeneticVariation BEFREE If confirmed in other studies, re-evaluation for JAK2 V617F mutation may be of help in early MPN detection and clinical management of SVT patients. 23916380

2013

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 GeneticVariation BEFREE In addition, our findings in JAK2(V617F)-negative SVT patients indicate an important role for the 46/1 haplotype in the etiology and diagnosis of SVT-related MPNs, independent of JAK2(V617F), that requires further exploration. 21364191

2011

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 GeneticVariation BEFREE In this study, the authors investigated the prevalence of MPN and JAK2 V617F mutation in Korean patients with SVT. 21435189

2011

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 GeneticVariation BEFREE We aimed to study patients with splanchnic vein thrombosis (SVT) and cerebral vein thrombosis (CVT) searching for JAK2 mutations. 21893442

2011

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 GeneticVariation BEFREE Anticoagulation is the treatment of choice for all SVT and proper treatment of the MPD is recommended in patients with SVT associated with the JAK2(V617F) mutation. 19478480

2009

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 GeneticVariation BEFREE JAK2 mutation was associated with increased risk of SVT (odds ratio, 53.98; 95% confidence interval, 13.10-222.45). 19273837

2009

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 GeneticVariation BEFREE We assessed the diagnostic and prognostic value of JAK2 and MPL515 mutations in 241 SVT patients (104 BCS, 137 PVT). 18250227

2008

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 GeneticVariation BEFREE Anticoagulation therapy combined with low-dose aspirin and proper treatment of the MPD is recommended in patients with SVT associated with the JAK2(V617F) mutation. 17687555

2007

Entrez Id: 10060
Gene Symbol: ABCC9
ABCC9
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO

Entrez Id: 54795
Gene Symbol: TRPM4
TRPM4
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO

Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO

Entrez Id: 6327
Gene Symbol: SCN2B
SCN2B
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO

Entrez Id: 783
Gene Symbol: CACNB2
CACNB2
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO

Entrez Id: 6324
Gene Symbol: SCN1B
SCN1B
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO

Entrez Id: 8260
Gene Symbol: NAA10
NAA10
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO

Entrez Id: 6261
Gene Symbol: RYR1
RYR1
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO

Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO

Entrez Id: 10021
Gene Symbol: HCN4
HCN4
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO

Entrez Id: 23171
Gene Symbol: GPD1L
GPD1L
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO

Entrez Id: 4000
Gene Symbol: LMNA
LMNA
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO

Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B
CUI: C0039240
Disease: Supraventricular tachycardia
Supraventricular tachycardia
0.100 Biomarker HPO