Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential 		0.030 GeneticVariation BEFREE The results show that polymorphisms in the Bcl 2, Bax, Fas, and Fas Ligand genes involved in the apoptotic pathways may not play a role in the pathogenesis of PV and ET. 29068570

2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential 		0.030 AlteredExpression BEFREE By real time PCR assay, we observed that A1, MCL1, BIK and BID, as well as A1, BCLW and BAK gene expression were increased in ET and PMF CD34+ cells respectively, while pro-apoptotic BAX and anti-apoptotic BCL2 mRNA levels were found to be lower in ET and PMF CD34+ cells respectively, in relation to controls. 22300941

2012
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential 		0.030 Biomarker BEFREE Patients treated with HU showed slightly higher pro-apoptotic Bax/Bcl-2 index than patients on ANA therapy, which may influence the better efficacy of HU therapy in ET. 22418850

2012