Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0041466
Disease: Typhoid Fever
Typhoid Fever
0.330 GeneticVariation BEFREE They also bind to the typhoid-resistant human leukocyte antigen (HLA) alleles DRB1*0401. 30547672

2019

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0041466
Disease: Typhoid Fever
Typhoid Fever
0.330 Biomarker CTD_human Imputation-based fine-mapping across the extended MHC region showed that the classical HLA-DRB1*04:05 allele (OR = 0.14, P = 2.60 × 10(-11)) could entirely explain the association at rs7765379, thus implicating HLA-DRB1 as a major contributor to resistance against enteric fever, presumably through antigen presentation. 25383971

2014

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0041466
Disease: Typhoid Fever
Typhoid Fever
0.330 GeneticVariation BEFREE Imputation-based fine-mapping across the extended MHC region showed that the classical HLA-DRB1*04:05 allele (OR = 0.14, P = 2.60 × 10(-11)) could entirely explain the association at rs7765379, thus implicating HLA-DRB1 as a major contributor to resistance against enteric fever, presumably through antigen presentation. 25383971

2014

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0041466
Disease: Typhoid Fever
Typhoid Fever
0.330 GeneticVariation BEFREE Haplotypes that were either protective (TNFA*1 [-308].DRB1*04) or predisposed individuals to typhoid fever (TNFA*2 [-308].DRB1*0301) were determined. 11120931

2001