Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.440 GeneticVariation BEFREE RAC1 P29 is the third most commonly mutated codon in human cutaneous melanoma, after BRAF V600 and NRAS Q61. 31257073

2019
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.440 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.440 GeneticVariation BEFREE Whole exome sequencing of cutaneous melanoma has led to the detection of P29 mutations in RAC1 in 5-9% of samples, but the role of RAC1 P29 mutations in melanoma biology remains unclear. 26176707

2015
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.440 GeneticVariation BEFREE Furthermore, we provide new results showing that RAC1, a gene recently found harboring UV-hallmark mutation in skin melanoma, is also mutated in uveal melanoma. 23981010

2014
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.440 GeneticVariation BEFREE Clinical and pathological associations of the activating RAC1 P29S mutation in primary cutaneous melanoma. 25043693

2014
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.440 CausalMutation CGI