Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration
0.030 GeneticVariation BEFREE There had been several studies on IL1RN polymorphism related with incidence of disc degeneration or back pain but, there had been no report on clinical features of lumbar HNP. 20581747

2010

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration
0.030 Biomarker BEFREE A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration. 16436110

2006

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration
0.030 GeneticVariation BEFREE To study the role of the interleukin-1 beta gene (IL1B) and the IL-1 receptor antagonist gene (IL1RN) in relation to the occurrence of radiographic osteoarthritis (ROA) in the hip, knee, and hand and disc degeneration of the spine. 15077300

2004