Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5030
Gene Symbol: P2RY4
P2RY4
CUI: C0162830
Disease: Dermatitis, Phototoxic
Dermatitis, Phototoxic 		0.030 Biomarker BEFREE Significant intracellular ROS generation was observed through DCFH2-DA/DHE assays along with a significant reduction in cell viability through MTT and NRU assays in photosensitized TCS. 30844667

2019
Entrez Id: 5030
Gene Symbol: P2RY4
P2RY4
CUI: C0162830
Disease: Dermatitis, Phototoxic
Dermatitis, Phototoxic 		0.030 Biomarker BEFREE This method has also been introduced in regulatory recommendations as part of 3T3-NRU-phototoxicity-assay, which was regulatory accepted in all EU member states in 2000 and in the OECD member states in 2004 as a test guideline (TG 432). 28470514

2017
Entrez Id: 5030
Gene Symbol: P2RY4
P2RY4
CUI: C0162830
Disease: Dermatitis, Phototoxic
Dermatitis, Phototoxic 		0.030 Biomarker BEFREE In conclusion, mDPRA plus photo-mDPRA and 3T3-NRU-PT seem to be preliminary non-animal test batteries for skin (photo)sensitization/phototoxicity assessment of chemicals, agrochemical formulations and their ingredients. 28389279

2017