×
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Centriacinar Emphysema
0.310
Biomarker
CTD_human
A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α.
25106431 2014
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Centriacinar Emphysema
0.310
Biomarker
CTD_human
A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α.
25106431 2014
×
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
Centriacinar Emphysema
0.310
GeneticVariation
BEFREE
The TGFB1 rs2241718 and MMP9 rs3918242 SNPs were associated with centrilobular emphysema (p = 0.022 and p = 0.008), and the TNF rs1800629 SNP with paraseptal emphysema (p = 0.017).
23734748 2013
×
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Centriacinar Emphysema
0.310
GeneticVariation
BEFREE
The TGFB1 rs2241718 and MMP9 rs3918242 SNPs were associated with centrilobular emphysema (p = 0.022 and p = 0.008), and the TNF rs1800629 SNP with paraseptal emphysema (p = 0.017).
23734748 2013
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Centriacinar Emphysema
0.310
GeneticVariation
BEFREE
The TGFB1 rs2241718 and MMP9 rs3918242 SNPs were associated with centrilobular emphysema (p = 0.022 and p = 0.008), and the TNF rs1800629 SNP with paraseptal emphysema (p = 0.017).
23734748 2013
×
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
Centriacinar Emphysema
0.310
Therapeutic
CTD_human
Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema.
12634787 2003
×
Entrez Id: 177
Gene Symbol: AGER
AGER
Centriacinar Emphysema
0.300
Biomarker
CTD_human
RAGE is a Critical Mediator of Pulmonary Oxidative Stress, Alveolar Macrophage Activation and Emphysema in Response to Cigarette Smoke.
30659203 2019
×
Entrez Id: 2006
Gene Symbol: ELN
ELN
Centriacinar Emphysema
0.300
Biomarker
CTD_human
A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α.
25106431 2014
×
Entrez Id: 4321
Gene Symbol: MMP12
MMP12
Centriacinar Emphysema
0.300
Biomarker
CTD_human
A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α.
25106431 2014
×
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
Centriacinar Emphysema
0.300
Biomarker
CTD_human
A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α.
25106431 2014
×
Entrez Id: 3694
Gene Symbol: ITGB6
ITGB6
Centriacinar Emphysema
0.300
Biomarker
CTD_human
Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema.
12634787 2003
×
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6
Centriacinar Emphysema
0.300
Biomarker
CTD_human
Association of CYP2A6 deletion polymorphism with smoking habit and development of pulmonary emphysema.
12832682 2003
×
Entrez Id: 4321
Gene Symbol: MMP12
MMP12
Centriacinar Emphysema
0.300
Biomarker
CTD_human
Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema.
12634787 2003
×
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
Centriacinar Emphysema
0.300
Biomarker
CTD_human
Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema.
10631150 2000
×
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
Centriacinar Emphysema
0.300
Biomarker
CTD_human
Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema.
9288046 1997
SERPINA1
Centriacinar Emphysema
0.300
Biomarker
CTD_human
Alpha 1-antitrypsin deficiency and emphysema caused by homozygous inheritance of non-expressing alpha 1-antitrypsin genes.
3485249 1986
×
Entrez Id: 5326
Gene Symbol: PLAGL2
PLAGL2
Centriacinar Emphysema
0.010
AlteredExpression
BEFREE
Previous study of transgenic mice with long-term expression of pleiomorphic adenoma gene-like 2 (PLAGL2 ), a surfactant protein C (SP-C) transactivator, in type II cells showed the manifestation of centrilobular emphysema in vivo.
21397355 2011
×
Entrez Id: 6440
Gene Symbol: SFTPC
SFTPC
Centriacinar Emphysema
0.010
Biomarker
BEFREE
Previous study of transgenic mice with long-term expression of pleiomorphic adenoma gene-like 2 (PLAGL2), a surfactant protein C (SP-C ) transactivator, in type II cells showed the manifestation of centrilobular emphysema in vivo.
21397355 2011