DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Chronic schizophrenia ×

Gene: IL1RN ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	3557
Gene Symbol:	IL1RN

IL1RN

CUI:	C0221765
Disease:	Chronic schizophrenia

Chronic schizophrenia

0.010

AlteredExpression

BEFREE

These findings suggest that chronic schizophrenia down-regulates IL-1RA production the prefrontal cortex, irrespective of its impact on the periphery.

12804791

2003