Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.240 GeneticVariation BEFREE The antitumor effect of RAF plus CDK4/6 inhibitors also needs to be evaluated in other subtypes of KRAS mutation in pancreatic cancer. 30271501

2018

Entrez Id: 5894
Gene Symbol: RAF1
RAF1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.240 GeneticVariation BEFREE A combinatorial strategy using YAP and pan-RAF inhibitors for treating KRAS-mutant pancreatic cancer. 28576749

2017

Entrez Id: 5894
Gene Symbol: RAF1
RAF1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.240 Biomarker BEFREE From these, we validated and further characterized novel gene fusions involving ROS1 tyrosine kinase in angiosarcoma (CEP85L/ROS1), SLC1A2 glutamate transporter in colon cancer (APIP/SLC1A2), RAF1 kinase in pancreatic cancer (ATG7/RAF1) and anaplastic astrocytoma (BCL6/RAF1), EWSR1 in melanoma (EWSR1/CREM), CDK6 kinase in T-cell acute lymphoblastic leukemia (FAM133B/CDK6), and CLTC in breast cancer (CLTC/VMP1). 23637631

2013

Entrez Id: 5894
Gene Symbol: RAF1
RAF1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.240 Biomarker BEFREE Furthermore, we were interested in determining if Raf-1 activation in pancreatic cancer led to subsequent activation of downstream effectors such as MAP kinase. 9202670

1997

Entrez Id: 5894
Gene Symbol: RAF1
RAF1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.240 Biomarker RGD Expression of c-myc, c-raf-1, and c-Ki-ras in azaserine-induced pancreatic carcinomas and growing pancreas in rats. 2278633

1990