Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.080 Biomarker BEFREE Elevated systemic levels of the matrix metalloproteinase inhibitor TIMP-1 correlate with clinical markers of cachexia in patients with chronic pancreatitis and pancreatic cancer. 29394913

2018
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.080 Biomarker BEFREE Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer. 28765154

2017
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.080 Biomarker BEFREE TIMP-1 antisense gene transfection attenuates the invasive potential of pancreatic cancer cells in vitro and inhibits tumor growth in vivo. 15910719

2005
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.080 Biomarker BEFREE This study demonstrates the potential role of TIMP-1 as a target in gene therapy for pancreatic cancer. 11792150

2002
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.080 Biomarker BEFREE The aim of this study was to investigate the effect of TIMP gene therapy on human pancreatic cancer. 11773977

2001
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.080 Biomarker BEFREE Analysis of TIMP-1 serum levels revealed significant increases in pancreatic cancer patients, but TIMP-1 by itself was inadequate as a serum marker for cancer. 9488584

1998
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.080 Biomarker BEFREE It is concluded that while overexpression of MMP7 and -11 may be countered by TIMP1, the aggressive phenotype of pancreatic carcinoma may occur because of overexpression of MMP2, activated by MTMMP and associated with a reduced expression of TIMP2. 9349239

1997
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.080 Biomarker BEFREE Both stromal and tumor cells appear to be the source of MMPs and TIMPs in human pancreatic cancer. 7635566

1995