Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 177
Gene Symbol: AGER
AGER
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration 		0.020 GeneticVariation BEFREE RESULTS The analysis of two single nucleotide polymorphisms (SNPs) in the RAGE gene showed that rs1800624 was associated with a 1.6-fold decreased risk for exudative AMD under the dominant model after adjustment for age (OR=0.616; 95% CI: 0.394-0.963; p=0.034) and each copy of allele T at rs1800624 was associated with a 1.4-fold decreased risk for exudative AMD development under the additive model after adjustment for age (OR=0.701; 95% CI: 0.510-0.962; p=0.028). 29317590

2018
Entrez Id: 177
Gene Symbol: AGER
AGER
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration 		0.020 Biomarker BEFREE Thus, we suggest that RAGE could be a potential therapeutic target for intracellular Aβ induced outer BRB breakdown in AMD. 26431165

2015