Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2194
Gene Symbol: FASN
FASN
CUI: C0243026
Disease: Sepsis
Sepsis 		0.030 Biomarker BEFREE Here, inhibition of fatty acid synthase by C75 improved neutrophil chemotaxis and increased the survival of mice with sepsis in cecal ligation puncture and lipopolysaccharide-induced septic shock models. 31427815

2019
Entrez Id: 2194
Gene Symbol: FASN
FASN
CUI: C0243026
Disease: Sepsis
Sepsis 		0.030 AlteredExpression BEFREE Our study provides evidence indicating that overexpressed miR-335-5p enhances autophagy by targeting FASN through activation of the AMPK/ULK1 signaling pathway working to alleviate the inflammatory response in septic mouse models, emphasizing the value of the functional upregulation of miR-335-5p as therapeutic strategy for sepsis. 29866515

2018
Entrez Id: 2194
Gene Symbol: FASN
FASN
CUI: C0243026
Disease: Sepsis
Sepsis 		0.030 Biomarker BEFREE UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis. 25574840

2015