Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
CUI: C0243026
Disease: Sepsis
Sepsis 		0.250 Biomarker BEFREE The Hepatic Glucocorticoid Receptor Is Crucial for Cortisol Homeostasis and Sepsis Survival in Humans and Male Mice. 29788135

2018
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
CUI: C0243026
Disease: Sepsis
Sepsis 		0.250 Biomarker BEFREE Examination of glucocorticoid receptor isoform abundance in tissues harvested from patients immediately after death from sepsis or nonseptic critical illness. 29787416

2018
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
CUI: C0243026
Disease: Sepsis
Sepsis 		0.250 Biomarker BEFREE In this study we investigated the role of the endothelial GR in sepsis in vivo and in vitro. 23248291

2013
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
CUI: C0243026
Disease: Sepsis
Sepsis 		0.250 Therapeutic RGD [The effect of low-dose hydrocortisone on the expression of glucocorticoid receptor alpha of the septic kidney and its protective effect on kidney in rat]. 21787473

2011
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
CUI: C0243026
Disease: Sepsis
Sepsis 		0.250 GeneticVariation BEFREE Our aim was to study changes in mRNA levels of three glucocorticoid receptor splice variants in neutrophils of children with sepsis. 19373457

2009
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
CUI: C0243026
Disease: Sepsis
Sepsis 		0.250 Biomarker BEFREE In conclusion, GR/NF-kappaB interaction affects CAR gene transcription through chromatin remodeling and provide a mechanistic explanation for the long-standing observation that inflammation and sepsis inhibit drug metabolism while inducing intrahepatic cholestasis or hyperbilirubinemia. 15382119

2004