Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 406913
Gene Symbol: MIR126
MIR126
CUI: C0243026
Disease: Sepsis
Sepsis
0.040 Biomarker BEFREE We previously showed that treatment with endothelial progenitor cells, which highly express microRNA-126 (miR-126), improved survival in mice subjected to cecal ligation and puncture (CLP) sepsis. miRNAs are important regulators of gene expression and cell function, play a major role in endothelial homeostasis, and may represent an emerging therapeutic modality. 30244405

2019

Entrez Id: 406913
Gene Symbol: MIR126
MIR126
CUI: C0243026
Disease: Sepsis
Sepsis
0.040 Biomarker BEFREE We previously found that endothelial progenitor cell (EPC) exosomes prevent endothelial dysfunction and lung injury in sepsis in part due to their encapsulation of miRNA-126. 30760290

2019

Entrez Id: 406913
Gene Symbol: MIR126
MIR126
CUI: C0243026
Disease: Sepsis
Sepsis
0.040 AlteredExpression BEFREE The up-regulation of miR-126 inhibited the septic inflammation and improved the prognosis of sepsis mice through the AKT/Rac1 signaling pathway. 30915758

2019

Entrez Id: 406913
Gene Symbol: MIR126
MIR126
CUI: C0243026
Disease: Sepsis
Sepsis
0.040 Biomarker BEFREE Thus, EPC exosomes prevent microvascular dysfunction and improve sepsis outcomes potentially through the delivery of miR-126. 29599080

2018