Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0243026
Disease: Sepsis
Sepsis 		0.040 Biomarker BEFREE Since polymorphonuclear neutrophils (PMNs) play a pivotal role in the early phase of sepsis, we evaluated the potential therapeutic effects of cholinesterase inhibitors on PMN functions during cecal ligation and puncture- (CLP-) induced sepsis and investigated the roles of AChE and BChE as inflammatory markers under standardized experimental conditions. 30804708

2019
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0243026
Disease: Sepsis
Sepsis 		0.040 AlteredExpression BEFREE Experimental sepsis induces sustained inflammation and acetylcholinesterase activity impairment in the hypothalamus. 30190086

2018
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0243026
Disease: Sepsis
Sepsis 		0.040 AlteredExpression BEFREE Furthermore, the present study aimed to elucidate the association between AChE activity and its expression at the NMJ during sepsis. 28849127

2017
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0243026
Disease: Sepsis
Sepsis 		0.040 AlteredExpression BEFREE In this study, we aimed to investigate whether the decreased AChE activity was related to oxidative stress by observing AChE activity in different grades of sepsis induced by caecal ligation and puncture (CLP). 29230271

2017