Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C0278510
Disease: Childhood Medulloblastoma
Childhood Medulloblastoma
0.340 AlteredExpression BEFREE Increased cytomegalovirus replication by 5-Azacytidine and viral-induced cytoplasmic expression of DNMT‑1 in medulloblastoma and endothelial cells. 29484388

2018

Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C0278510
Disease: Childhood Medulloblastoma
Childhood Medulloblastoma
0.340 Biomarker BEFREE Within this review, we summarize the main preclinical studies regarding epigenetic targets (such as HDAC, SIRT, BET, EZH2, G9a, LSD1, and DNMT) inhibitors in medulloblastoma. 30560106

2018

Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C0278510
Disease: Childhood Medulloblastoma
Childhood Medulloblastoma
0.340 Biomarker BEFREE We found that in HDAC1 and DNMT1 overexpressing medulloblastoma-derived cells, cell death was induced under various epigenetic drug conditions tested. 28429280

2017

Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C0278510
Disease: Childhood Medulloblastoma
Childhood Medulloblastoma
0.340 AlteredExpression BEFREE In conclusion, DNMT1, DNMT3A and DNMT3B are highly expressed in human medulloblastoma samples, suggesting that promoter hypermethylation may play a role in medulloblastoma development. 27543768

2016

Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C0278510
Disease: Childhood Medulloblastoma
Childhood Medulloblastoma
0.340 Biomarker CTD_human Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice. 19155313

2009