DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Serous cystadenocarcinoma ovary ×

Gene: PIK3CA ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	5290
Gene Symbol:	PIK3CA

PIK3CA

CUI:	C0279663
Disease:	Serous cystadenocarcinoma ovary

Serous cystadenocarcinoma ovary

0.120

Biomarker

BEFREE

LPAR1 regulates the development of intratumoral heterogeneity in ovarian serous cystadenocarcinoma by activating the PI3K/AKT signaling pathway.

31384176

2019

Entrez Id:	5290
Gene Symbol:	PIK3CA

PIK3CA

CUI:	C0279663
Disease:	Serous cystadenocarcinoma ovary

Serous cystadenocarcinoma ovary

0.120

GeneticVariation

CLINVAR

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

26619011

2016

Entrez Id:	5290
Gene Symbol:	PIK3CA

PIK3CA

CUI:	C0279663
Disease:	Serous cystadenocarcinoma ovary

Serous cystadenocarcinoma ovary

0.120

AlteredExpression

BEFREE

Activation of the PI3K/AKT pathway mediates FSH-stimulated VEGF expression in ovarian serous cystadenocarcinoma.

18574502

2008