Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
CUI: C0280449
Disease: secondary acute myeloid leukemia
secondary acute myeloid leukemia
0.020 Biomarker BEFREE In AML, CPX-351 offers a new induction chemotherapy for secondary AML that prolongs survival, and venetoclax and IDH inhibitors are efficacious and well tolerated. 30848394

2019

Entrez Id: 3418
Gene Symbol: IDH2
IDH2
CUI: C0280449
Disease: secondary acute myeloid leukemia
secondary acute myeloid leukemia
0.020 GeneticVariation BEFREE Enriched in secondary acute myeloid leukemia (sAML; in comparison to high-risk MDS), FLT3, PTPN11, WT1, IDH1, NPM1, IDH2 and NRAS mutations (type 1) tended to be newly acquired, and were associated with faster sAML progression and a shorter overall survival time. 27992414

2017