Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.030 Biomarker BEFREE The present results show that PAI-1 overexpression is associated with nonhomologous end-joining DNA repair down-regulation (low Ku70/80 expression) and with increased p53 and cyclin D1 expression, and they suggest that PAI-1 plays a role in the tumor behavior in cervical carcinoma. 23111469

2012
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.030 Biomarker BEFREE The combined polymorphism of uPA/PAI-1 might diminish the ability of PAI-1 to inhibiting cervical cancer carcinogenesis when PAI-1 alone as the role of inhibitor. 22354580

2012
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.030 AlteredExpression BEFREE Our results show that the (enhanced) expression of PAI-1 by carcinoma cells is correlated with worse (overall and disease-free) survival of patients with cancer of the uterine cervix. 15386352

2004