Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57016
Gene Symbol: AKR1B10
AKR1B10
CUI: C0342257
Disease: Complications of Diabetes Mellitus
Complications of Diabetes Mellitus 		0.020 AlteredExpression BEFREE Humans exhibit three members of the AKR1B subfamily: AKR1B1 (aldose reductase, participates in diabetes complications), AKR1B10 (overexpressed in several cancer types), and the recently described AKR1B15. 31028727

2019
Entrez Id: 57016
Gene Symbol: AKR1B10
AKR1B10
CUI: C0342257
Disease: Complications of Diabetes Mellitus
Complications of Diabetes Mellitus 		0.020 Biomarker BEFREE Our results show that XN, IX and 8-PN are potent uncompetitive, tight-binding inhibitors of human aldose reductase AKR1B1 (K<sub>i</sub> = 15.08 μM, 0.34 μM, 0.71 μM) and of human AKR1B10 (K<sub>i</sub> = 20.11 μM, 2.25 μM, 1.95 μM). 29532688

2018