DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Malignant neoplasm of prostate ×

Gene: NECTIN2 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	5819
Gene Symbol:	NECTIN2

NECTIN2

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.310

AlteredExpression

BEFREE

CD276, PVR, and NECTIN2 were highly expressed in PC.

30614027

2019

Entrez Id:	5819
Gene Symbol:	NECTIN2

NECTIN2

CUI:	C0376358
Disease:	Malignant neoplasm of prostate

Malignant neoplasm of prostate

0.310

Biomarker

CTD_human

CD276 and the alternative checkpoint inhibition PVR/NECTIN2/CD226/TIGIT pathway emerged as relevant to PC checkpoint inhibition target development.

30614027

2019