×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
Adolescent idiopathic scoliosis
0.160
GeneticVariation
BEFREE
Moreover, GPR126 (ADGRG6 ) mutations are associated with human diseases, like adolescent idiopathic scoliosis , lung disease, bladder cancer, and intellectual disability.
31215653 2019
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
Adolescent idiopathic scoliosis
0.160
AlteredExpression
BEFREE
Asymmetric expression of GPR126 in the convex/concave side of the spine is associated with spinal skeletal malformation in adolescent idiopathic scoliosis population.
31079250 2019
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
Adolescent idiopathic scoliosis
0.160
GeneticVariation
GWASCAT
Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese.
31417091 2019
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
Adolescent idiopathic scoliosis
0.160
GeneticVariation
BEFREE
Genetic polymorphisms of GPR126 are functionally associated with PUMC classifications of adolescent idiopathic scoliosis in a Northern Han population.
29363878 2018
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
Adolescent idiopathic scoliosis
0.160
GeneticVariation
GWASCAT
Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci.
30395268 2018
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
Adolescent idiopathic scoliosis
0.160
GeneticVariation
BEFREE
A genetic association study of GPR126 gene with adolescent idiopathic scoliosis (AIS) in the Chinese population.
28198779 2017
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
Adolescent idiopathic scoliosis
0.160
Biomarker
BEFREE
The genetic association of GPR126 gene and AIS might provide valuable insights into the pathogenesis of adolescent idiopathic scoliosis .
25479386 2015
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
Adolescent idiopathic scoliosis
0.160
GeneticVariation
GWASDB
Identification of a susceptibility locus for severe adolescent idiopathic scoliosis on chromosome 17q24.3.
24023777 2013
×
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6
Adolescent idiopathic scoliosis
0.160
GeneticVariation
BEFREE
Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis .
23666238 2013
×
Entrez Id: 7421
Gene Symbol: VDR
VDR
Adolescent idiopathic scoliosis
0.140
GeneticVariation
BEFREE
Association between polymorphisms in vitamin D receptor gene and adolescent idiopathic scoliosis : a meta-analysis.
29728923 2018
×
Entrez Id: 7421
Gene Symbol: VDR
VDR
Adolescent idiopathic scoliosis
0.140
GeneticVariation
BEFREE
Association of vitamin D receptor BsmI rs1544410 and ApaI rs7975232 polymorphisms with susceptibility to adolescent idiopathic scoliosis : A systematic review and meta-analysis.
29480871 2018
×
Entrez Id: 7421
Gene Symbol: VDR
VDR
Adolescent idiopathic scoliosis
0.140
GeneticVariation
GWASCAT
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
30019117 2018
×
Entrez Id: 7421
Gene Symbol: VDR
VDR
Adolescent idiopathic scoliosis
0.140
GeneticVariation
BEFREE
Correlations of VDR and VDBP genetic polymorphisms with susceptibility to adolescent idiopathic scoliosis and efficacy of brace treatment.
27856225 2016
×
Entrez Id: 7421
Gene Symbol: VDR
VDR
Adolescent idiopathic scoliosis
0.140
GeneticVariation
BEFREE
Polymorphism in vitamin D receptor is associated with bone mineral density in patients with adolescent idiopathic scoliosis .
20361340 2010
×
Entrez Id: 54796
Gene Symbol: BNC2
BNC2
Adolescent idiopathic scoliosis
0.120
GeneticVariation
GWASCAT
Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese.
31417091 2019
×
Entrez Id: 54796
Gene Symbol: BNC2
BNC2
Adolescent idiopathic scoliosis
0.120
GeneticVariation
GWASCAT
Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci.
30395268 2018
×
Entrez Id: 54796
Gene Symbol: BNC2
BNC2
Adolescent idiopathic scoliosis
0.120
Biomarker
BEFREE
An international meta-analysis confirms the association of BNC2 with adolescent idiopathic scoliosis .
29549362 2018
×
Entrez Id: 54796
Gene Symbol: BNC2
BNC2
Adolescent idiopathic scoliosis
0.120
GeneticVariation
BEFREE
Genetic variant of BNC2 gene is functionally associated with adolescent idiopathic scoliosis in Chinese population.
28342042 2017
×
Entrez Id: 54796
Gene Symbol: BNC2
BNC2
Adolescent idiopathic scoliosis
0.120
GeneticVariation
GWASCAT
A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis.
26211971 2015
×
Entrez Id: 5077
Gene Symbol: PAX3
PAX3
Adolescent idiopathic scoliosis
0.110
AlteredExpression
BEFREE
Abnormal paravertebral muscles development is associated with abnormal expression of PAX3 in adolescent idiopathic scoliosis .
31832874 2020
×
Entrez Id: 28
Gene Symbol: ABO
ABO
Adolescent idiopathic scoliosis
0.110
Biomarker
BEFREE
A recent large-scale genome-wide association study reported three novel loci in CDH13, ABO , and SOX6 genes associated with adolescent idiopathic scoliosis (AIS) in Japanese population.
30994600 2019
×
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
Adolescent idiopathic scoliosis
0.110
Biomarker
BEFREE
A recent large-scale genome-wide association study reported three novel loci in CDH13, ABO, and SOX6 genes associated with adolescent idiopathic scoliosis (AIS) in Japanese population.
30994600 2019
×
Entrez Id: 5077
Gene Symbol: PAX3
PAX3
Adolescent idiopathic scoliosis
0.110
GeneticVariation
GWASCAT
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
30019117 2018
×
Entrez Id: 55553
Gene Symbol: SOX6
SOX6
Adolescent idiopathic scoliosis
0.110
GeneticVariation
GWASCAT
Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci.
30395268 2018
×
Entrez Id: 10752
Gene Symbol: CHL1
CHL1
Adolescent idiopathic scoliosis
0.110
GeneticVariation
GWASCAT
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
30019117 2018