×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
Biomarker
BEFREE
Single-Immunoglobulin Interleukin-1-Related Receptor regulates vulnerability to TLR4 -mediated necrotizing enterocolitis in a mouse model.
28846670 2018
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
Biomarker
BEFREE
Inflammation and Apoptosis: Dual Mediator Role for Toll-like Receptor 4 in the Development of Necrotizing Enterocolitis .
27849634 2017
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
Biomarker
BEFREE
Toll-like receptor 4 -mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis .24519940 2014
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
Biomarker
CTD_human
Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling.
23650378 2013
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
Biomarker
BEFREE
A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis .
23455503 2013
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
Biomarker
BEFREE
Our lead compound, C34, is a 2-acetamidopyranoside (MW 389) with the formula C17H27NO9, which inhibited TLR4 in enterocytes and macrophages in vitro, and reduced systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis .
23776545 2013
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
Biomarker
BEFREE
Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice.
22796522 2012
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
Biomarker
RGD
Ileal immune dysregulation in necrotizing enterocolitis: role of CD40/CD40L in the pathogenesis of disease.
21240009 2011
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
Biomarker
BEFREE
Toll-like receptor-4 inhibits enterocyte proliferation via impaired beta-catenin signaling in necrotizing enterocolitis .19786028 2010
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
AlteredExpression
BEFREE
Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitis .
20976181 2010
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
Biomarker
RGD
Changes in intestinal Toll-like receptors and cytokines precede histological injury in a rat model of necrotizing enterocolitis.
19608731 2009
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
AlteredExpression
BEFREE
Reciprocal expression and signaling of TLR4 and TLR9 in the pathogenesis and treatment of necrotizing enterocolitis .
19109197 2009
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
Biomarker
LHGDN
Reciprocal expression and signaling of TLR4 and TLR9 in the pathogenesis and treatment of necrotizing enterocolitis .
19109197 2009
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
Biomarker
LHGDN
A critical role for TLR4 in the pathogenesis of necrotizing enterocolitis by modulating intestinal injury and repair.
17878380 2007
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Necrotizing Enterocolitis
0.600
GeneticVariation
BEFREE
Genetic polymorphisms of CD14, toll-like receptor 4 , and caspase-recruitment domain 15 are not associated with necrotizing enterocolitis in very low birth weight infants.
16385250 2006