×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
GeneticVariation
BEFREE
CONCLUSIONS D allele and DD genotype of ACE gene are possible genetic markers for the risk of LVH in Uighur but not Han hypertension-OSAHS patients.
31064975
2019
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
Biomarker
BEFREE
Other potential causes include angiotensin-converting enzyme inhibitor use, environmental triggers, tobacco use, chronic obstructive pulmonary disease, and obstructive sleep apnea .
29094873
2017
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
GeneticVariation
BEFREE
Our study demonstrated that TNF-α 308 G/A , 5-HTT LPR, and 5-HTT-VNTR polymorphisms were associated with OSAS risk, whereas little association was observed between 5-HTR2A 102C/T , 5-HTR2A A1438G , ACE I /D, or LEPR-Gln 223Arg polymorphism and risk of OSAS in the Chinese population.
25917830
2015
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
AlteredExpression
BEFREE
Collectively, genetically-reduced serum ACE activity might be a causal risk factor for OSAS .
26486181
2015
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
GeneticVariation
BEFREE
ACE polymorphism I/D had no statistically significant association with increased OSA risk, but the II genotype of ACE may be a risk factor for OSA with hypertension in Asians.
24271410
2014
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
Biomarker
RGD
Atrial fibrosis in a chronic murine model of obstructive sleep apnea: mechanisms and prevention by mesenchymal stem cells.
24775918
2014
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
Biomarker
BEFREE
We also found that there was no significant association between ACE I /D and OSAHS severity risk.No publication biases were observed.
23359027
2013
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
Biomarker
BEFREE
The frequencies of II genotype (OR = 1.8, 95 % CI 1.26-2.60, p = 0.001) and I allele (OR = 1.4, 95 % CI 1.13-1.69, p = 0.001) of ACE gene were found to be significantly increased in patients with OSA as compared to patients without OSA .
23371888
2013
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
GeneticVariation
BEFREE
We aimed to undertake a meta-analysis of existing studies exploring the association of ACE I /D polymorphisms with the risk of OSA and hypertension.
22183487
2012
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
GeneticVariation
BEFREE
We conclude that ACE I /D gene polymorphism is not a genetic risk factor for OSAS in Turkish patients.
20449805
2010
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
GeneticVariation
BEFREE
Our results suggest that II and ID genotypes of the ACE gene increase the risk of developing OSAS in the Turkish population.
20182789
2010
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
GeneticVariation
BEFREE
We therefore tested the hypothesis that ACE polymorphism influences OSA severity.
19482546
2009
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
GeneticVariation
BEFREE
An interaction analysis including sex, ACE I /D polymorphism (DD and ID versus II), and OSA identified a significant interaction between OSA and the ACE I /D polymorphism: odds ratio (OR) 6.3, 95% confidence interval (CI) 1.8-22.5, P = 0.004 as well as between OSA and sex: OR 3.3, 95% CI 1.1-9.6, P = 0.033.
17351369
2007
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
GeneticVariation
BEFREE
The ACE deletion allele may protect against hypertension in the setting of obstructive sleep apnea .
17520798
2007
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
GeneticVariation
LHGDN
The association of angiotensin converting enzyme (ACE) polymorphisms with sleep apnea and hypertension.
17520798
2007
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
AlteredExpression
BEFREE
ACE activity was higher in OSAS patients (53.9+/-2.5 IU.L(-1)) than in healthy controls (42.4+/-3.1 IU.L(-1), p<0.01).
11401071
2001
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
GeneticVariation
BEFREE
The distribution of ACE gene I/D allele and genotypes were analyzed in the subject population, as was an OSA pedigree.
11016793
2000
×
Entrez Id:
1636
Gene Symbol:
ACE
ACE
Sleep Apnea, Obstructive
0.300
GeneticVariation
BEFREE
Angiotensin I-converting enzyme gene polymorphism in Chinese patients with obstructive sleep apnea syndrome .
11601275
1999