Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.050 Biomarker BEFREE These results suggested that the combinational therapy based on doxorubicin-loaded PCL-Pluronic micelle and miR-34a may provide a reasonable strategy for improving the outcome of esophageal cancer treatment. 30256436

2018

Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.050 Biomarker BEFREE our data showed that miR-34a acted as a tumor suppressor in human esophageal cancer. 26944831

2016

Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.050 PosttranslationalModification BEFREE The hypermethylation of miR-34a CpG_8.9 was associated with the advanced UICC stage III/IV of the esophageal cancers, and the hypermethylation of CpG_8.9 and CpG_5 of miR-34a was significantly correlated with lymph node metastasis. 24528540

2014

Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.050 AlteredExpression BEFREE In addition, we found that overexpression of NF-kappaB p65 could not successfully induce miR-34a expression in esophageal cancer cell lines with mutant p53 or decreased p53. 22292433

2012

Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.050 Biomarker BEFREE In addition, the role of miR-34a in esophageal cancer also warrants further study. 20309880

2011