Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.060 Biomarker BEFREE In both <i>MYC</i> and <i>ERBB2</i> amplified tumour cells, ibrutinib downregulated ERK-mediated signal transduction, cMYC Ser-62 phosphorylation and levels of MYC protein, and elicited G<sub>1</sub> cell cycle arrest and apoptosis, suggesting that this drug could be used to treat biomarker-selected groups of patients with oesophageal cancer. 28830912

2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.060 Biomarker BEFREE However, its roles in c-MYC pathway regulation and esophageal cancer tumorigenesis have yet not been elucidated. 28476684

2017
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.060 AlteredExpression BEFREE In conclusion, the expression patterns of c-MYC, MAX and the MAD family were shown to be deregulated in the oesophageal cancer model. 18493233

2008
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.060 AlteredExpression BEFREE The myc target gene Mina53 was reported to be overexpressed in esophageal cancer with a poor prognosis. 17803656

2007
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.060 Biomarker BEFREE Positive C-MYC staining was detected mainly in the cytoplasm of esophageal cancer cells. 16490593

2006
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.060 Biomarker BEFREE Amplification of the EGF receptor and c-myc genes in human esophageal cancers. 2459070

1988