Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		0.320 Biomarker BEFREE Studies of mutations in the tumour suppressor genes <i>TSC1, TSC2,</i> and <i>STK11,</i> activating the mtor (mammalian target of rapamycin) pathway, might support their role in the pathogenesis of thyroid cancer. 29089812

2017
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		0.320 Biomarker BEFREE Additionally, knockdown of TSC2, the upstream regulatory molecule of mTOR pathway, or treatment of rapamycin, the mTOR inhibitor, could abolish the effects of metformin to regulate thyroid cancer cell proliferation, migration, EMT, and mTOR pathway molecules. 25854169

2015
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		0.320 CausalMutation CGI