Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0595995
Disease: Idiopathic scoliosis
Idiopathic scoliosis 		0.060 GeneticVariation BEFREE To determine whether the ERα gene polymorphisms correlate with idiopathic scoliosis. 24961754

2014
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0595995
Disease: Idiopathic scoliosis
Idiopathic scoliosis 		0.060 GeneticVariation BEFREE PvuII SNP (C/T rs2234693) of ESR1 was described to be associated with the occurrence of IS in the Chinese population; however, two replication studies did not confirm the findings. 24155906

2013
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0595995
Disease: Idiopathic scoliosis
Idiopathic scoliosis 		0.060 GeneticVariation BEFREE Studies have shown that idiopathic scoliosis is related to genetic factors, such as XbaI site polymorphism of the estrogen receptor alpha gene. 19337134

2009
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0595995
Disease: Idiopathic scoliosis
Idiopathic scoliosis 		0.060 GeneticVariation BEFREE Furthermore, we extracted DNA from white blood cells of IS patients and their relatives until the third generation in order to examine estrogen receptor alpha polymorphisms, considering this tool a plausible molecular marker for IS prognosis. 19406238

2009
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0595995
Disease: Idiopathic scoliosis
Idiopathic scoliosis 		0.060 GeneticVariation BEFREE However, to our knowledge, the relationship of estrogen receptor gene polymorphisms and the individual susceptibility to idiopathic scoliosis has not been studied. 16648749

2006
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0595995
Disease: Idiopathic scoliosis
Idiopathic scoliosis 		0.060 GeneticVariation BEFREE Association between estrogen receptor gene polymorphisms and curve severity of idiopathic scoliosis. 12438984

2002