Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3640
Gene Symbol: INSL3
INSL3
CUI: C0848558
Disease: Hypospadias
Hypospadias 		0.020 Biomarker BEFREE The abnormal development of fetal Leydig cells could lead to the reduction of androgen and insulin-like 3, thus causing the male reproductive tract anomalies in male neonates, including cryptorchidism and hypospadias. 31780936

2019
Entrez Id: 3640
Gene Symbol: INSL3
INSL3
CUI: C0848558
Disease: Hypospadias
Hypospadias 		0.020 Biomarker BEFREE Using a case-control design, we show that cryptorchidism and hypospadias are both significantly associated with increased amniotic concentration of INSL3 during gestational weeks 13-16, and some, though not all steroid biomarkers. 29740335

2018