Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 645682
Gene Symbol: POU5F1P4
POU5F1P4
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.070 AlteredExpression BEFREE OCT4 mRNA was overexpressed in effusions compared to solid specimens (p = 0.046), whereas SOX9 was overexpressed in the ovarian tumors compared to effusions and solid metastases (p = 0.003). 30904337

2019

Entrez Id: 645682
Gene Symbol: POU5F1P4
POU5F1P4
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.070 Biomarker BEFREE Further, OCT-4 was found to be putative target of miR-99-3p in ovarian cancer and inhibition of OCT-4 had similar effects as that of miR-299 inhibition on cell migration and invasion. 29758200

2018

Entrez Id: 645682
Gene Symbol: POU5F1P4
POU5F1P4
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.070 Biomarker BEFREE Our results indicate that hPaf1/PD2 is overexpressed in OCSCs and maintains the self-renewal of OCSCs through its interaction with OCT3/4; thus, hPaf1/PD2 may be a potential therapeutic target to overcome tumor relapse in OC. 28122356

2017

Entrez Id: 645682
Gene Symbol: POU5F1P4
POU5F1P4
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.070 Biomarker BEFREE OCT4 controls mitotic stability and inactivates the RB tumor suppressor pathway to enhance ovarian cancer aggressiveness. 28319064

2017

Entrez Id: 645682
Gene Symbol: POU5F1P4
POU5F1P4
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.070 AlteredExpression BEFREE We also examined OCT4 expression in surgical specimens of ovarian cancer. 23921511

2013

Entrez Id: 645682
Gene Symbol: POU5F1P4
POU5F1P4
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.070 Biomarker BEFREE Lin28 regulates BMP4 and functions with Oct4 to affect ovarian tumor microenvironment. 23255092

2013

Entrez Id: 645682
Gene Symbol: POU5F1P4
POU5F1P4
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.070 Biomarker BEFREE Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer. 20101213

2010