Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C1096293
Disease: Macroangiopathy
Macroangiopathy 		0.020 Biomarker BEFREE If confirmed by further investigations, the results of this pilot study suggest that iloprost, infused for both brief and long periods, is able to reduce the cardiovascular risk factor PAI-1, increases free walking capacity and does not affect glucometabolic control and blood pressure in type-2 diabetic patients complicated by macroangiopathy. 10501817

1999
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C1096293
Disease: Macroangiopathy
Macroangiopathy 		0.020 GeneticVariation BEFREE Using multivariate logistic regression analyses, we investigated the independent or synergistic effects of the ACE I/D and PAI-1 4G/5G polymorphisms on the development of diabetic nephropathy and macroangiopathy in 208 patients with non-insulin dependent diabetes mellitus (NIDDM) over a 15 year period. 9844142

1998