Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 104909134
Gene Symbol: LINC02210-CRHR1
LINC02210-CRHR1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.150 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. 29942085

2018
Entrez Id: 104909134
Gene Symbol: LINC02210-CRHR1
LINC02210-CRHR1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.150 Biomarker BEFREE Effects of corticotropin-releasing hormone receptor 1 SNPs on major depressive disorder are influenced by sex and smoking status. 27544317

2016
Entrez Id: 104909134
Gene Symbol: LINC02210-CRHR1
LINC02210-CRHR1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.150 AlteredExpression BEFREE Recent clinical and preclinical studies, using genetic screening and transgenic rodents, respectively, suggest a major role of the CRF1 gene, and the central expression of CRF1 receptor protein in determining an individual's risk of developing MDD. 26271720

2015
Entrez Id: 104909134
Gene Symbol: LINC02210-CRHR1
LINC02210-CRHR1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.150 Biomarker BEFREE As a major mediator of the stress response, corticotropin-releasing-hormone receptor 1 (CRHR1) has been demonstrated to be an important contributor to the pathogenesis of MDD. 23529111

2013
Entrez Id: 104909134
Gene Symbol: LINC02210-CRHR1
LINC02210-CRHR1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.150 Biomarker BEFREE The aim of this study is to examine the single and combined effects of CRH receptor 1 (CRHR1) and BDNF genes in recurrent major depressive disorder (MDD). 22194899

2011
Entrez Id: 104909134
Gene Symbol: LINC02210-CRHR1
LINC02210-CRHR1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.150 Biomarker BEFREE A nonpeptide CRF1 receptor antagonist has also been shown to reduce symptoms of major depression in an open-label clinical trial. 16122764

2006