Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901

2019

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 GeneticVariation GWASCAT Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. 29700475

2018

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 Biomarker BEFREE No association of ESR2 G×E interaction with MDD was found in the reproductive group. 27814959

2017

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 GeneticVariation BEFREE Estrogen receptor alpha (ESR1) and beta (ESR2) are known to regulate gene expression and estrogen response in areas of the brain associated with major depression and are unlikely to be correlated with exogenous factors that may influence depression. 26169989

2015

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 GeneticVariation BEFREE The results suggest that shorter length of AR and ER beta gene microsatellites might influence the onset of MDD in female adolescents, a further elucidation of the mechanisms is warranted. 17365134

2007

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.430 Biomarker PSYGENET The results suggest that shorter length of AR and ER beta gene microsatellites might influence the onset of MDD in female adolescents, a further elucidation of the mechanisms is warranted. 17365134

2007