Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.090 Biomarker BEFREE Colony stimulating factor-1 receptor promotes proliferation, migration and invasion in the human nasopharyngeal carcinoma 6-10B cell line via the phosphoinositide 3-kinase/Akt pathway. 30061942

2018

Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.090 Biomarker BEFREE Moreover, we report a signaling pathway involving CSF-1R and JAG1 that sustains osteosarcoma cell migration and invasion. 28469954

2017

Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.090 Biomarker BEFREE In addition, CSF-1R overexpression significantly enhanced NSCLC cells mobility, invasion and epithelial-mesenchymal transition (EMT) process, whereas silencing CSF-1R inhibits these phenotypes. 29218239

2017

Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.090 Biomarker BEFREE Results showed that A549 cells express CSF1/CSF1R; CSF1 increased their proliferation and invasion, whereas soluble CSF1R inhibited invasion. 24468794

2014

Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.090 Biomarker BEFREE This crosstalk enforces aggressive CD44(+)IGF1R(+)CSF1R(+) LC phenotypes, including extranodal invasion and chemoresistance. 24651014

2014

Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.090 Biomarker BEFREE Phosphorylation of CSF-1R Y721 mediates its association with PI3K to regulate macrophage motility and enhancement of tumor cell invasion. 21610095

2011

Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.090 Biomarker BEFREE Constitutive activation of the extracellular signal-regulated kinase (ERK) pathway also enhanced PDEF-induced motility and invasion, suggesting that activation of the ERK/mitogen-activated protein kinase by ErbB2 and CSF-1R/CSF-1 can cooperate with PDEF to promote motility and invasion. 16357167

2005

Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.090 Biomarker BEFREE Transfection of wild-type CSF1R into HC11 mammary epithelial cells (HC11-CSF1R) renders the transfectants capable of in vitro local invasion and in vivo tumorigenesis. 14767486

2004

Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.090 GeneticVariation BEFREE In contrast, CSF-1 had no effect on invasion in the CSF-1R-negative MCF-7 cell line. 1535551

1992