Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 Biomarker BEFREE We analyzed cancer-specific biclusters and found that the PI3K/Akt signaling pathway is strongly enriched with targets of a few miRNAs in breast cancer and diffuse large B-cell lymphoma. 30820547

2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 Biomarker BEFREE BEBT-908: A novel potent PI3K/HDAC inhibitor against diffuse large B-cell lymphoma. 28756223

2017
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 Biomarker BEFREE PI3Kδ inhibitor idelalisib in combination with BTK inhibitor ONO/GS-4059 in diffuse large B cell lymphoma with acquired resistance to PI3Kδ and BTK inhibitors. 28178345

2017
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 AlteredExpression BEFREE PI3Kδ inhibition causes feedback activation of PI3Kα in the ABC subtype of diffuse large B-cell lymphoma. 29137222

2017
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 AlteredExpression BEFREE PIK3CD promoted proliferation in diffuse large B cell lymphoma through upregulation of c-myc. 27448819

2016
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 Biomarker BEFREE SPIB is a novel prognostic factor in diffuse large B-cell lymphoma that mediates apoptosis via the PI3K-AKT pathway. 27348272

2016
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 Biomarker BEFREE MCL-1-independent mechanisms of synergy between dual PI3K/mTOR and BCL-2 inhibition in diffuse large B cell lymphoma. 26460954

2015
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 Biomarker BEFREE MicroRNA-21 plays an oncogenic role by targeting FOXO1 and activating the PI3K/AKT pathway in diffuse large B-cell lymphoma. 25909227

2015
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 Biomarker BEFREE Inhibition of the PI3K/Akt/mTOR signaling pathway in diffuse large B-cell lymphoma: current knowledge and clinical significance. 25215588

2014
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 PosttranslationalModification BEFREE Moreover, we detected a similarly functioning prosurvival pathway involving phosphorylated CD19 and PI3K-dependent Erk phosphorylation in human diffuse large B-cell lymphoma cell lines. 24938766

2014
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 Biomarker BEFREE Frequent copy number variations of PI3K/AKT pathway and aberrant protein expressions of PI3K subunits are associated with inferior survival in diffuse large B cell lymphoma. 24418330

2014
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 Biomarker BEFREE Quantitative proteomics reveals that miR-155 regulates the PI3K-AKT pathway in diffuse large B-cell lymphoma. 22609116

2012
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		0.100 AlteredExpression BEFREE Leptin receptor expression and its association with PI3K/AKT signaling pathway in diffuse large B-cell lymphoma. 20443680

2010